5-Amino-1MQ

The Complete Guide to Dosage, Benefits, and Research

1. 5-Amino-1MQ Dosage Chart | Quick Breakdown

PurposeDosage RangeFrequencyAdministration
General Use50-150 mg1-3x dailyOral capsules
Weight Loss100-150 mg1-2x dailyOral capsules
Research10-150 mg/kg/dayAs per protocolOral/Injectable (animal studies)

2. What is 5-Amino-1MQ?

5-Amino-1MQ is a small molecule drug designed to inhibit the enzyme nicotinamide N-methyltransferase (NNMT). Key points:

  • Chemical formula: C10H11N2+
  • Structure: Quinoline ring with an amino group at position 5 and a methyl group at position 1
  • Developed as a selective NNMT inhibitor
  • Primarily studied for its effects on metabolism and weight loss
  • Not FDA-approved; currently used in research settings

3. 5-Amino-1MQ Mechanism of Action

5-Amino-1MQ works through several mechanisms:

  • 1 Inhibits NNMT, an enzyme predominantly active in fat tissue
  • 2 Increases nicotinamide adenine dinucleotide (NAD+) levels
  • 3 Activates sirtuin-1 (SIRT1), also known as "the longevity gene"
  • 4 Enhances cellular metabolism and energy expenditure
  • 5 Promotes fat burning while preserving muscle mass
  • 6 Regulates energy expenditure in fat cells
  • 7 May increase NAD+ and S-adenosyl methionine (SAM) concentrations in fat cells

4. Research Applications and Potential Benefits of 5-Amino-1MQ

5-Amino-1MQ and Weight Loss

  • Promotes fat loss while preserving muscle mass
  • May reverse diet-induced obesity
  • Enhances metabolic rate and fat burning

5-Amino-1MQ and Metabolic Health

  • Potential treatment for type 2 diabetes and metabolic syndrome
  • May improve insulin sensitivity
  • Could lower cholesterol levels and improve blood sugar control

5-Amino-1MQ and Muscle Health

  • Enhances aged muscle regeneration
  • May promote muscle growth and recovery
  • Potential benefits for sarcopenia (age-related muscle loss)

5-Amino-1MQ and Cancer

  • Shows promise in combating various cancer types
  • May disrupt energy supply to cancer cells
  • Potential to enhance effectiveness of cancer therapies

5-Amino-1MQ and Anti-Aging

  • Activates SIRT1, associated with longevity
  • May have anti-inflammatory properties
  • Potential to improve overall healthspan

5. 5-Amino-1MQ Dosage Guide

Dosing 5-Amino-1MQ for General Use

  • Typical dose: 50-150 mg per day
  • Often divided into 1-3 doses

Dosing 5-Amino-1MQ for Weight Loss

  • Higher dose: 100-150 mg per day
  • Usually divided into 1-2 doses

Dosing 5-Amino-1MQ for Research

  • Dose range in animal studies: 10-150 mg/kg/day
  • Human equivalent doses not established

6. How to Mix and Administer 5-Amino-1MQ

5-Amino-1MQ is typically available in pre-measured capsules:

  • No mixing required for oral capsules
  • For research purposes, may be reconstituted with appropriate solvents
  • Always follow manufacturer's instructions for handling and administration

7. 5-Amino-1MQ Administration Methods

Oral Administration

  • Most common method for human use
  • Take capsules on an empty stomach
  • May be taken once daily or divided into multiple doses

Injectable Administration (Research Only)

  • Used in animal studies
  • Not typically used in human applications

8. 5-Amino-1MQ Combinations and Interactions

Limited data on combinations. Potential synergies with:

  • NAD+ boosters
  • Other metabolic enhancers
  • Exercise regimens for enhanced fat loss

Always research potential interactions before combining substances.

9. Where to Buy 5-Amino-1MQ Online | 2024 Edition

5-Amino-1MQ is primarily available for research purposes. It's crucial to source from reputable suppliers that provide certificates of analysis and third-party testing results.

10. Is 5-Amino-1MQ Safe?

Generally considered to have a favorable safety profile in animal studies:

  • No significant adverse effects reported in preclinical trials
  • Human safety data is limited

Potential side effects may include:

  • Nausea
  • Headache
  • Increased appetite (due to increased metabolic rate)
  • Not approved by the FDA for human use
  • Legal status varies by country and jurisdiction
  • Often restricted to research or medical use
  • In the US, it's legal to possess for research purposes but not for human consumption
  • Always check local laws before purchasing or using 5-Amino-1MQ

12. 5-Amino-1MQ Storage and Handling

  • Store in a cool, dry place away from direct light
  • Keep at room temperature (20-25°C or 68-77°F)
  • Protect from moisture
  • Keep out of reach of children
  • Use within the expiration date

13. Frequently Asked Questions (FAQ)

How long does it take to see effects from 5-Amino-1MQ?
Can 5-Amino-1MQ be used for bodybuilding?
Is 5-Amino-1MQ safe for long-term use?
Can women use ipamorelin?
How does 5-Amino-1MQ compare to other weight loss supplements?

14. 5-Amino-1MQ Dosage | Final Verdict

  • 5-Amino-1MQ shows promise as a novel compound for metabolic health, weight management, and potentially anti-aging applications. The typical dosage range of 50-150 mg per day appears effective for most research applications. Its unique mechanism of NNMT inhibition offers a new approach to tackling obesity and metabolic disorders.However, its use should be approached cautiously due to limited long-term human safety data and varying legal status worldwide. As with any experimental compound, thorough research and professional consultation are essential before use. The potential of 5-Amino-1MQ in weight management, metabolic health, and age-related conditions warrants further investigation, particularly in larger, long-term human trials.

15. References

  • 1 Neelakantan H, et al. (2019). Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochemical Pharmacology, 164, 165-180.
  • 2 Kannt A, et al. (2018). A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Scientific Reports, 8(1), 3660.
  • 3 Kraus D, et al. (2014). Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature, 508(7495), 258-262.
  • 4 Hong S, et al. (2015). Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nature Medicine, 21(8), 887-894.
  • 5 Ulanovskaya OA, et al. (2013). NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. Nature Chemical Biology, 9(5), 300-306.