Purpose | Dosage Range | Frequency | Administration |
---|---|---|---|
General Use | 1000-2000 mcg | 1-2x weekly | Subcutaneous injection |
Bodybuilding | 2000-3000 mcg | 1-2x weekly | Subcutaneous injection |
Anti-Aging | 1000-1500 mcg | 1-2x weekly | Subcutaneous injection |
Research | 30-60 mcg/kg | 1-2x weekly | Subcutaneous injection |
2. What is CJC-1295??
Also known as DAC:GRF (Drug Affinity Complex:Growth Hormone-Releasing Factor)
Composed of 30 amino acids
Molecular formula: C152H252N44O42
Molecular weight: 3367.954 g/mol
Developed by ConjuChem Biotechnologies
Modified form of GHRH (1-29) with improved pharmacokinetics, especially half-life
Binds to GHRH receptors in the anterior pituitary gland
Stimulates the pulsatile release of growth hormone
Increases the amplitude of growth hormone pulses
Enhances production of insulin-like growth factor 1 (IGF-1)
Extends the half-life of GHRH through bioconjugation with albumin
Maintains more consistent blood levels of growth hormone
Increases plasma GH levels by 2- to 10-fold for 6 days or longer
Elevates plasma IGF-1 levels by 0.5- to 3-fold for 9 to 11 days
Potential to reduce body fat
May increase lean muscle mass
Could improve overall body composition
May accelerate wound healing
Potential to enhance recovery from exercise and injuries
May improve sleep quality and duration
Potential to enhance deep sleep phases
Possible improvements in memory and mental clarity
Potential neuroprotective effects
Typical dose: 1000-2000 mcg per week
Often divided into 1-2 doses
Higher dose: 2000-3000 mcg per week
Usually divided into 1-2 doses
Lower dose: 1000-1500 mcg per week
Often administered 1-2 times weekly
Dose range: 30-60 mcg per kg of body weight
Typically administered 1-2 times weekly
Use bacteriostatic water to reconstitute the lyophilized powder
Add water slowly, allowing it to trickle down the side of the vial
Gently swirl the vial to mix, avoid shaking to prevent protein denaturation
Calculate the correct dosage based on concentration (e.g., 2000 mcg/ml)
Use sterile syringes and needles for each injection
Recommended needle size: 29-31 gauge, 1/2 inch length
Common injection sites: abdomen (2 inches away from navel), thigh, or upper arm
Rotate injection sites to prevent irritation
Administer on an empty stomach or at least 2 hours after eating
For optimal results, avoid eating for 1-2 hours post-injection
Popular combination for enhanced GH release
Typical dosage: 1000 mcg CJC-1295 + 300 mcg Ipamorelin, administered together
May increase GH release synergistically
May provide complementary effects
Dosages should be adjusted when combined (typically 1000 mcg CJC-1295 + 100-200 mcg GHRP)
Injection site reactions (redness, swelling)
Headaches
Flushing
Nausea
Water retention
Increased insulin sensitivity
Not approved by the FDA for human use
Legal status varies by country and jurisdiction
Often restricted to research or medical use
Banned by WADA for competitive athletes
In the US, it's legal to possess for research purposes but not for human consumption
Always check local laws before purchasing or using CJC-1295
Store lyophilized powder at room temperature (20-25°C or 68-77°F) away from light
Once reconstituted, store in the refrigerator (2-8°C or 36-46°F)
Use within 30 days after reconstitution
Do not freeze reconstituted CJC-1295
Always use sterile techniques when handling
Results may vary, but some users report noticeable changes within 4-8 weeks of consistent use. Improved sleep and recovery may be noticed within the first few weeks, while changes in body composition typically take 2-3 months to become apparent.
While not primarily a weight loss drug, CJC-1295 may contribute to fat loss as part of its effects on body composition and metabolism.
Long-term safety data is limited. Use should be monitored by a healthcare professional. Some studies have shown safe use for up to 12 months, but regular health check-ups and blood tests are recommended.
CJC-1295 DAC includes a Drug Affinity Complex that extends its half-life to about 8 days, compared to the 30-minute half-life of regular CJC-1295.
CJC-1295 shows promise as a potent growth hormone secretagogue with potential benefits for body composition, recovery, and anti-aging. The typical dosage range of 1000-3000 mcg per week appears effective for most applications, with specific dosages tailored to individual goals and responses.
Its ability to increase growth hormone levels for extended periods makes it an attractive option for those seeking the benefits of increased GH without the need for daily injections. However, its use should be approached cautiously due to limited long-term safety data and varying legal status.
Always consult with a healthcare professional before starting any peptide regimen, and ensure regular monitoring of health markers during use. As research continues, our understanding of CJC-1295's full potential and optimal use protocols may evolve.
Teichman SL, et al. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805.
Ionescu M, Frohman LA. (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. Journal of Clinical Endocrinology & Metabolism, 91(12), 4792-4797.
Sackmann-Sala L, et al. (2009). Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Hormone & IGF Research, 19(6), 471-477.
Alba M, et al. (2006). Once-weekly administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analogue, normalizes growth in growth hormone-deficient rats. Growth Hormone & IGF Research, 16(5-6), 326-334.
Jetté L, et al. (2005). Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification
Disclaimer
Peptideresearcher.com contains information about products intended for research and laboratory use only, unless otherwise explicitly stated. All content is for educational purposes and is not meant to substitute for professional medical advice. Peptideresearcher.com strives to ensure that all information presented is accurate and complies with national and international standards, but it is not guaranteed. The content provided is not intended to diagnose, treat, cure, or prevent any disease or condition.
Peptideresearcher.com does not offer medical diagnoses or prescriptions. Any product information shared is solely for research purposes and should be used by qualified professionals only. We advise all users to consult with a healthcare professional before using any peptides, supplements, or medications mentioned on this site. All opinions expressed are those of the individual authors and may not reflect the opinions of Peptideresearcher.com.
Copyright 2024 - Peptide Researcher
Your access to Peptideresearcher.com is subject to our Terms of Use