Purpose | Dosage | Frequency | Duration |
---|---|---|---|
General Use | 2-5 mg | 2x weekly | 4-8 weeks |
Injury Recovery | 5-10 mg | 2x weekly | 4-6 weeks |
Maintenance | 2-5 mg | 1x weekly | Ongoing |
TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4 (Tβ4). Key points:
Discovered in the 1970s
Present in virtually all human and animal cells
Plays a crucial role in cell building and tissue repair
Molecular weight: 4963 Da
Sequence: 43 amino acids
Actin Regulation: TB-500 binds to actin, promoting cell migration and proliferation.
Angiogenesis: It stimulates the formation of new blood vessels, enhancing blood flow to injured areas.
Anti-Inflammatory Effects: TB-500 reduces inflammation, aiding in faster recovery.
Stem Cell Activation: It may activate adult stem cells, promoting tissue regeneration.
Wound Healing: TB-500 upregulates healing-specific genes, accelerating wound closure.
Accelerates healing of muscle, tendon, and ligament injuries
Reduces recovery time for athletes
Improves flexibility and reduces muscle stiffness
Promotes formation of new blood vessels
May aid in repair of heart tissue after injury
Potential to stimulate hair growth and prevent hair loss
Accelerates wound closure
Improves the quality of healing, potentially reducing scarring
May aid in corneal wound healing
Potential applications in treating dry eye syndrome
Typical dose: 2-5 mg, twice weekly
Duration: 4-8 weeks
Higher dose: 5-10 mg, twice weekly
Duration: 4-6 weeks, then taper to maintenance dose
2-5 mg, once weekly
Can be continued long-term
Vial of TB-500 (lyophilized powder)
Bacteriostatic water
Sterile syringe and needle
Alcohol swabs
For a 5mg vial of TB-500, add 2ml of bacteriostatic water to create a concentration of 2.5mg per ml.
Sterilize the vial tops with alcohol swabs
Draw the correct amount of bacteriostatic water into the syringe
Slowly inject the water into the TB-500 vial, aiming for the side to avoid foaming
Gently swirl the vial until the peptide is fully dissolved. Do not shake vigorously.
Most common method
Inject into fatty tissue, rotating injection sites
Can be used for more direct delivery to muscle tissue
May cause more discomfort than subcutaneous injections
Popular combination for enhanced healing
TB-500: 2-5 mg twice weekly
BPC-157: 250 mcg twice daily
May enhance muscle growth and recovery
TB-500: 2-5 mg twice weekly
GH: As prescribed by a healthcare professional
Reputable sources for TB-500 include:
Peptide Sciences
Pure Rawz
Swiss Chems
Always verify the legitimacy and quality of the source before purchasing.
Generally considered safe with minimal reported side effects
Long-term human studies are limited
Potential side effects may include:
Headaches
Fatigue
Nausea
Joint pain
Hair growth in undesired areas
Not approved by the FDA for human use
Legal to purchase for research purposes in many countries, including the US
Banned by WADA for competitive athletes
Legal status varies by country:
USA: Legal for research purposes
EU: Varies by country, generally not approved for human use
Canada: Not approved for sale or use in humans
Australia: Considered a prescription-only medicine
Store lyophilized (powder) TB-500 in a cool, dry place away from direct light
Once reconstituted, store in a refrigerator (2-8°C or 36-46°F)
Use reconstituted TB-500 within 30 days
Do not freeze reconstituted TB-500
Keep away from heat and direct sunlight
Always use sterile techniques when handling and administering TB-500
Many users report noticeable improvements within 2-4 weeks, with optimal results typically seen after 4-8 weeks of consistent use.
While not directly anabolic, TB-500 may aid in muscle recovery and injury prevention, potentially supporting bodybuilding efforts.
TB-500 has shown potential for various injuries, particularly those involving soft tissues. However, its effectiveness may vary depending on the specific injury and individual factors.
While some concerns have been raised about TB-500's potential to promote cancer growth, current research is inconclusive. It's crucial to consult with a healthcare professional, especially if you have a history of cancer.
Standard drug tests do not typically screen for TB-500. However, it is banned by WADA for competitive athletes.
TB-500 shows promising potential for tissue repair, injury recovery, and various health applications. A typical dosage range of 2-5 mg twice weekly appears effective for most uses, with the option to increase dosage for acute injuries. While generally well-tolerated, it's crucial to approach TB-500 use with caution due to its experimental nature. Always consult with a healthcare professional before starting any new supplement regimen, especially one involving peptides like TB-500. Proper dosing, administration, and adherence to safety guidelines are key to maximizing potential benefits while minimizing risks.
Goldstein, A. L., et al. (2012). Thymosins: Clinical promise after initial disappointment. Expert Opinion on Biological Therapy, 12(11), 1377-1387.
Philp, D., et al. (2003). Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development. Mechanisms of Ageing and Development, 124(10-12), 1139-1146.
Sosne, G., et al. (2002). Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury. Experimental Eye Research, 74(2), 293-299.
Crockford, D., et al. (2010). Thymosin β4: structure, function, and biological properties supporting current and future clinical applications. Annals of the New York Academy of Sciences, 1194, 179-189.
Mora, C. A., et al. (2019). Thymosin β4: A Multi-Functional Regenerative Peptide. Basic Properties and Clinical Applications. Expert Opinion on Biological Therapy, 19(6), 501-514.
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