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Epithalon: The Complete Guide to Dosage, Benefits, and Research in 2024

Epithalon Dosage Chart | Quick Breakdown

Purpose Dosage Range Frequency Administration
General Anti-Aging 5-10 mg Once daily for 10-20 days Subcutaneous injection
Sleep Improvement 5-10 mg Once daily before bed Subcutaneous injection
Immune Enhancement 10 mg Once daily for 10 days Subcutaneous injection
Research 0.1-10 mg/kg As per protocol Subcutaneous/Intraperitoneal

2. What is Epithalon?

Epithalon, also known as Epitalon, is a synthetic tetrapeptide:

  • Chemical formula: C14H22N4O5

  • Molecular weight: 390.35 g/mol

  • Sequence: Ala-Glu-Asp-Gly

  • Developed by Vladimir Khavinson in the 1980s

  • Derived from Epithalamin, a polypeptide extract from bovine pineal gland

  • Known for its potential anti-aging and telomere-lengthening properties

3. Epithalon Mechanism of Action

Epithalon works through several mechanisms:

  1. Stimulates the production of telomerase, an enzyme that extends telomeres

  2. Regulates melatonin production in the pineal gland

  3. Modulates neuroendocrine functions

  4. Enhances antioxidant activity

  5. Influences gene expression related to cell cycle and apoptosis

  6. Regulates circadian rhythms

  7. Potentially affects the immune system function

4. Research Applications and Potential Benefits of Epithalon

Epithalon and Longevity

  • Potential to extend lifespan by preserving telomere length

  • May slow down cellular aging processes

Epithalon and Sleep Regulation

  • Improves melatonin production

  • Enhances sleep quality and regulates circadian rhythms

Epithalon and Immune Function

  • Potential to boost immune system activity

  • May enhance resistance to infections

Epithalon and Cognitive Function

  • Possible neuroprotective effects

  • May improve memory and cognitive performance in aging individuals

Epithalon and Cardiovascular Health

  • Potential to improve heart health markers

  • May reduce risk of age-related cardiovascular diseases

Epithalon and Cancer

  • Possible anti-tumor effects

  • May enhance the efficacy of some cancer treatments

Epithalon and Retinal Health

  • Potential to improve retinal function

  • May help in treating or preventing age-related eye disorders

5. Epithalon Dosage Guide

Dosing Epithalon for General Anti-Aging

  • Typical dose: 5-10 mg per day

  • Administered once daily for 10-20 days

  • Cycles repeated 2-4 times per year

Dosing Epithalon for Sleep Improvement

  • Dose: 5-10 mg per day

  • Administered once daily before bedtime

Dosing Epithalon for Immune Enhancement

  • Dose: 10 mg per day

  • Administered once daily for 10 days

Dosing Epithalon for Research

  • Dose range: 0.1-10 mg per kg of body weight

  • Frequency depends on research protocol

6. How to Mix and Administer Epithalon

  1. Reconstitute lyophilized Epithalon with bacteriostatic water

  2. Use sterile injection materials

  3. Calculate dosage based on body weight or research protocol

  4. Draw correct amount into insulin syringe

  5. Administer via subcutaneous injection

7. Epithalon Administration Methods

Subcutaneous Injection

  • Most common method for research and general use

  • Inject into fatty tissue of abdomen or thigh

Intraperitoneal Injection

  • Used in some animal studies

  • Not typically used in human applications

8. Epithalon Combinations and Interactions

Epithalon + Melatonin

  • May enhance sleep-regulating effects

Epithalon + Antioxidants

  • Potential synergistic effects on cellular health

Always research potential interactions before combining substances.

  • Dose: 10 mg per day

  • Administered once daily for 10 days

9. Where to Buy Epithalon Online | 2024 Edition

Epithalon is primarily available for research purposes. It's crucial to source from reputable suppliers that provide certificates of analysis and third-party testing results.

10. Is Epithalon Safe?

Generally considered to have a favorable safety profile in studies, but potential side effects include:

  • Injection site reactions

  • Headache

  • Dizziness

  • Fatigue

Long-term safety data in humans is limited. Use should be under medical supervision.

11. Is Epithalon Legal?

  • Not approved by the FDA for human use

  • Legal status varies by country and jurisdiction

  • Often restricted to research or medical use

  • In the US, it's legal to possess for research purposes but not for human consumption

12. Epithalon Storage and Handling

  • Store lyophilized powder at -20°C (-4°F)

  • Once reconstituted, store in refrigerator (2-8°C or 36-46°F)

  • Use within 30 days after reconstitution

  • Protect from light and excessive heat

  • Always use sterile techniques when handling

13. Frequently Asked Questions (FAQ)

How long does it take to see effects from Epithalon?

Effects may vary, but some users report improvements in sleep and energy within 1-2 weeks. Long-term effects on aging may take months to years to become apparent.

Can Epithalon be used for anti-aging purposes?

Yes, Epithalon is primarily studied for its potential anti-aging effects, particularly its ability to potentially extend telomere length.

  1. Dose: 10 mg per day

  2. Administered once daily for 10 days

How does Epithalon compare to other anti-aging peptides?

 Epithalon is unique in its ability to potentially stimulate telomerase production. It may have synergistic effects when combined with other anti-aging interventions.

Are there any long-term risks associated with Epithalon use?

 Long-term safety data is limited. Potential risks include disruption of natural hormone production and possible effects on cell division. More research is needed to fully understand long-term effects.

14. Epithalon Dosage | Final Verdict

Epithalon shows promise as a potential anti-aging peptide with a range of possible benefits, including telomere preservation, improved sleep quality, and enhanced immune function. The typical dosage range of 5-10 mg administered once daily for 10-20 days, repeated 2-4 times per year, appears to be the most commonly used protocol in research settings.However, its use should be approached cautiously due to limited long-term human safety data and varying legal status worldwide. As with any experimental compound, thorough research and professional consultation are essential before use. The potential of Epithalon in longevity and age-related conditions warrants further investigation, particularly in larger, long-term human trials.

15. References

  1. Khavinson VK, et al. (2003). Peptide promotes overcoming of the division limit in human somatic cell. Bulletin of Experimental Biology and Medicine, 135(6), 590-592.

  2. Anisimov VN, et al. (2003). Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology, 4(4), 193-202.

  3. Korkushko OV, et al. (2004). Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects with accelerated aging. Bulletin of Experimental Biology and Medicine, 138(5), 441-443.

  4. Khavinson V, et al. (2009). Peptides and ageing. Neuroendocrinology Letters, 30(3), 343-355.

  5. Khavinson VK, Morozov VG. (2003). Peptides of pineal gland and thymus prolong human life. Neuroendocrinology Letters, 24(3-4), 233-240.

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